Extracellular Matrix and The Liver: Approach to Gene Therapy

Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discussesnew strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapyapproaches.The chapters are divided into six sections as follows:* Basic Science of Extracellular Matrix* Cells Responsible for Extracellular Matrix Production* Activation Mechanism of Hepatic Cells and Signal Transduction* Basic Science for Extracellular Matrix Metabolism including Enzymes and their Inhibitors* Matrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases * New Strategies for the treatment of Liver Cirrhosis Key Features* Discusses the possibility of gene therapy for liver cirrhosis* Includes information on new aspects of hepatic stellate cells* Written by top experts in basic science and clinical hepatology